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The use of programs, like Kaplan-Meier Plotter, that correlate the expression levels of genes involved in the metabolism of amino acids with the prognosis of different tumors might indicate the candidate tumors for these adjunctive therapies, especially when more than one gene is associated with the same outcome (good or bad prognosis), similar to a gene enrichment score, but for prognosis

the beneficial effects of AMPK activation are attenuated when PARP-1 is activated